Wayne Blackshear had 28 points for the Cardinals
Montrezl Harrell had 24 points to lead the Cardinals to the regional finals.
The Cardinals reach the Sweet Sixteen for the fourth straight season.
Terry Rozier led the Cardinals with 20 points in loss to North Carolina.
Mangok Mathiang made a 15-footer with 2.5 seconds left to give No. 16 Louisville the lead
Louisville Men's Basketball v Michigan State | NCAA Elite 8
Louisville takes on Michigan State in the Elite 8 of the NCAA Tournament
Louisville Men's Basketball | NCAA Regional Final Media Day
Louisville Men's Basketball v NC State | Ncaa Sweet 16
NCAA Basketball: NCAA Tournament-East Regional-Louisville vs North Carolina State (USATSI)